Suzuki Laboratory
Division of Molecular Oncology
Nagoya University Graduate School of Medicine

/ EN

Achievements

* equal contribution
# corresponding author

2024 【Progress Report】

  1. Matsumoto K, Ikliptikawati DK, Makiyama K, Mochizuki K, Tobita M, Kobayashi I, Voon DC, Lim K, Ogawa K, Kashiwakura I, Suzuki HI, Yoshino H, Wong RW, Hazawa M#. Phase-separated super-enhancers confer an innate radioresistance on genomic DNA.
    J Radiat Res. 2024 Jul 22;65(4):482-490. doi: 10.1093/jrr/rrae044.
  2. Enokido T, Horie M, Yoshino S, Suzuki HI, Matsuki R, Brunnström H, Micke P, Nagase T, Saito A, Miyashita N#.
    Distinct microRNA signature and suppression of ZFP36L1 define ASCL1-positive lung adenocarcinoma.
    Mol Cancer Res. 2024 Jan 2;22(1):29-40. doi: 10.1158/1541-7786.MCR-23-0229.

2023　【Progress Report】

  1. Suzuki MM*, Iijima K*, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y#.
    TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.
    Nat Commun. 2023 Aug 22;14(1):4521. doi: 10.1038/s41467-023-40243-8.
  2. Suzuki HI#.
    Roles of MicroRNAs in Disease Biology.
    JMA J. 2023 Apr 14;6(2):104-113. doi: 10.31662/jmaj.2023-0009. Epub 2023 Mar 24.
  3. Kawamata M#, Suzuki HI#, Kimura R, Suzuki A#.
    Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs.
    Nat Biomed Eng. 2023 May;7(5):672-691. doi: 10.1038/s41551-023-01011-7. Epub 2023 Apr 10.
  4. Komatsu S, Kitai H, Suzuki HI#.
    Network Regulation of microRNA Biogenesis and Target Interaction.
    Cells. 2023 Jan 13;12(2):306. doi: 10.3390/cells12020306.

2022

  1. Kitai H, Kato N#, Ogami K, Komatsu S, Watanabe Y, Yoshino S, Koshi E, Tsubota S, Funahashi Y, Maeda T, Furuhashi K, Ishimoto T, Kosugi T, Maruyama S, Kadomatsu K, Suzuki HI#.
    Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis.
    BMC Biol. 2022 Nov 11;20(1):248. doi: 10.1186/s12915-022-01447-4.
  2. Yan M, Komatsu N, Muro R, Huynh NC, Tomofuji Y, Okada Y, Suzuki HI, Takaba H, Kitazawa R, Kitazawa S, Pluemsakunthai W, Mitsui Y, Satoh T, Okamura T, Nitta T, Im SH, Kim CJ, Kollias G, Tanaka S, Okamoto K, Tsukasaki M, Takayanagi H#.
    ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts.
    Nat Immunol. 2022 Sep;23(9):1330-1341. doi: 10.1038/s41590-022-01285-0. Epub 2022 Aug 23.
  3. Shimamura Y, Furuhashi K#, Tanaka A, Karasawa M, Nozaki T, Komatsu S, Watanabe K, Shimizu A, Minatoguchi S, Matsuyama M, Sawa Y, Tsuboi N, Ishimoto T, Suzuki HI, Maruyama S.
    Mesenchymal stem cells exert renoprotection via extracellular vesicle-mediated modulation of M2 macrophages and spleen-kidney network.
    Commun Biol. 2022 Jul 28;5(1):753. doi: 10.1038/s42003-022-03712-2.
  4. Miyakawa K, Miyashita N, Horie M, Terasaki Y, Tanaka H, Urushiyama H, Fukuda K, Okabe Y, Ishii T, Kuwahara N, Suzuki HI, Nagase T, Saito A#.
    ASCL1 regulates super-enhancer-associated miRNAs to define molecular subtypes of small cell lung cancer.
    Cancer Sci. 2022 Nov;113(11):3932-3946. doi: 10.1111/cas.15481. Epub 2022 Aug 30.
  5. Yoshino S, Suzuki HI#.
    The molecular understanding of super-enhancer dysregulation in cancer.
    Nagoya J Med Sci. 2022 May;84(2):216-229. doi: 10.18999/nagjms.84.2.216.
  6. Suzuki HI#, Onimaru K.
    Biomolecular Condensates in Cancer Biology.
    Cancer Sci. 2022 Feb;113(2):382-391. doi: 10.1111/cas.15232. Epub 2021 Dec 14.

2021

  1. Ogami K, Suzuki HI#.
    Nuclear RNA Exosome and Pervasive Transcription: Dual Sculptors of Genome Function.
    Int J Mol Sci. 2021 Dec 13;22(24):13401. doi: 10.3390/ijms222413401.

2020

  1. Li Y, Que L, Fukano K, Koura M, Kitamura K, Zheng X, Kato T, Aly HH, Watashi K, Tsukuda S, Aizaki H, Watanabe N, Sato Y, Suzuki T, Suzuki HI, Hosomichi K, Kurachi M, Wakae K#, Muramatsu M#.
    MCPIP1 reduces HBV-RNA by targeting its epsilon structure.
    Sci Rep. 2020 Nov 27;10(1):20763. doi: 10.1038/s41598-020-77166-z.
  2. Miyashita N, Horie M, Suzuki HI, Saito M, Mikami Y, Okuda K, Boucher RC, Suzukawa M, Hebisawa A, Saito A#, Nagase T.
    FOXL1 Regulates Lung Fibroblast Function via Multiple Mechanisms.
    Am J Respir Cell Mol Biol. 2020 Dec;63(6):831-842. doi: 10.1165/rcmb.2019-0396OC.
  3. Tomofuji Y*, Takaba H*, Suzuki HI, Benlaribi R, Martinez CDP, Abe Y, Morishita Y, Okamura T, Taguchi A, Kodama T, Takayanagi H#.
    Chd4 choreographs self-antigen expression for central immune tolerance.
    Nat Immunol. 2020 Aug;21(8):892-901. doi: 10.1038/s41590-020-0717-2. Epub 2020 Jun 29.
  4. Ochi Y, Kon A, Sakata T, Nakagawa MM, Nakazawa N, Kakuta M, Kataoka K, Koseki H, Nakayama M, Morishita D, Tsuruyama T, Saiki R, Yoda A, Okuda R, Yoshizato T, Yoshida K, Shiozawa Y, Nannya Y, Kotani S, Kogure Y, Kakiuchi N, Nishimura T, Makishima H, Malcovati L, Yokoyama A, Takeuchi K, Sugihara E, Sato TA, Sanada M, Takaori-Kondo A, Cazzola M, Kengaku M, Miyano S, Shirahige K, Suzuki HI#, Ogawa S#.
    Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.
    Cancer Discov. 2020 Jun;10(6):836-853. doi: 10.1158/2159-8290.CD-19-0982. Epub 2020 Apr 5.

2019

  1. Matsuyama H, Suzuki HI#.
    Systems and Synthetic microRNA Biology: From Biogenesis to Disease Pathogenesis.
    Int J Mol Sci. 2019 Dec 24;21(1). pii: E132. doi: 10.3390/ijms21010132.
  2. Tominaga K, Suzuki HI#.
    TGF-β Signaling in Cellular Senescence and Aging-Related Pathology.
    Int J Mol Sci. 2019 Oct 10;20(20). pii: E5002. doi: 10.3390/ijms20205002.
  3. Kelly TJ*, Suzuki HI*, Zamudio JR, Suzuki M, Sharp PA#.
    Sequestration of microRNA-mediated target repression by the Ago2-associated RNA binding protein FAM120A.
    RNA. 2019 Oct;25(10):1291-1297. doi: 10.1261/rna.071621.119. Epub 2019 Jul 9.
  4. Akatsu Y*, Takahashi N*, Yoshimatsu Y*, Kimuro S, Muramatsu T, Katsura A, Maishi N, Suzuki HI, Inazawa J, Hida K, Miyazono K, Watabe T#.
    Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk1.
    Mol Oncol. 2019 Aug;13(8):1706-1724. doi: 10.1002/1878-0261.12504. Epub 2019 Jun 19.
  5. Grigelioniene G*, Suzuki HI*, Taylan F, Mirzamohammadi F, Borochowitz ZU, Ayturk UM, Tzur S, Horemuzova E, Lindstrand A, Weis MA, Grigelionis G, Hammarsjö A, Marsk E, Nordgren A, Nordenskjöld M, Eyre DR, Warman ML, Nishimura G, Sharp PA, Kobayashi T#.
    Gain-of-function mutation of microRNA-140 in human skeletal dysplasia.
    Nat Med. 2019 Apr;25(4):583-590. doi: 10.1038/s41591-019-0353-2. Epub 2019 Feb 25.

2018

  1. Souma K, Shichino S, Hashimoto S, Ueha S#, Tsukui T, Nakajima T, Suzuki HI, Shand FHW, Inagaki Y, Nagase T, Matsushima K.
    Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis.
    Sci Rep. 2018 Nov 9;8(1):16642. doi: 10.1038/s41598-018-34839-0.
  2. Gao A*, Shrinivas K*, Lepeudry P, Suzuki HI, Sharp PA#, Chakraborty AK#.
    Evolution of weak cooperative interactions for biological specificity.
    Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11053-E11060. doi: 10.1073/pnas.1815912115. Epub 2018 Nov 7.
  3. Miyashita N, Horie M, Suzuki HI, Yoshihara M, Djureinovic D, Persson J, Brunnström H, Lindskog C, Elfving H, Micke P, Saito A#, Nagase T.
    An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas.
    J Thorac Oncol. 2018 Nov;13(11):1676-1691. doi: 10.1016/j.jtho.2018.07.096. Epub 2018 Aug 16.
  4. Suzuki HI#, Horie M, Mihira H, Saito A. Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling. J Vis Exp. 2018 Aug 3;(138). doi: 10.3791/57577.
  5. Suzuki HI#.
    MicroRNA Control of TGF-β Signaling.
    Int J Mol Sci. 2018 Jun 28;19(7). pii: E1901. doi: 10.3390/ijms19071901.
  6. Suzuki HI, Spengler RM, Grigelioniene G, Kobayashi T, Sharp PA#.
    Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics.
    Nat Genet. 2018 May;50(5):657-661. doi: 10.1038/s41588-018-0104-1. Epub 2018 Apr 16.
  7. Chiu AC*, Suzuki HI*, Wu X, Mahat DB, Kriz AJ, Sharp PA#.
    Transcriptional Pause Sites Delineate Stable Nucleosome-Associated Premature Polyadenylation Suppressed by U1 snRNP.
    Mol Cell. 2018 Feb 15;69(4):648-663.e7. doi: 10.1016/j.molcel.2018.01.006. Epub 2018 Feb 1.
  8. Lai HH, Li JN, Wang MY, Huang HY, Croce CM, Sun HL, Lyu YJ, Kang JW, Chiu CF, Hung MC, Suzuki HI, Chen PS#.
    HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
    J Clin Invest. 2018 Feb 1;128(2):625-643. doi: 10.1172/JCI89212. Epub 2017 Dec 18.

2017

  1. Nissim L, Wu MR, Pery E, Binder-Nissim A, Suzuki HI, Stupp D, Wehrspaun C, Tabach Y, Sharp PA, Lu TK#.
    Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy.
    Cell. 2017 Nov 16;171(5):1138-1150.e15. doi: 10.1016/j.cell.2017.09.049. Epub 2017 Oct 19.
  2. Horie M*, Miyashita N*, Mikami Y, Noguchi S, Yamauchi Y, Suzukawa M, Fukami T, Ohta K, Asano Y, Sato S, Yamaguchi Y, Ohshima M, Suzuki HI, Saito A#, Nagase T.
    TBX4 is involved in the super-enhancer-driven transcriptional programs underlying features specific to lung fibroblasts.
    Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L177-L191. doi: 10.1152/ajplung.00193.2017. Epub 2017 Sep 28.
  3. Suzuki HI#, Katsura A, Mihira H, Horie M, Saito A, Miyazono K.
    Regulation of TGF-β-mediated endothelial-mesenchymal transition by microRNA-27.
    J Biochem. 2017 May 1;161(5):417-420. doi: 10.1093/jb/mvx017.
  4. Suzuki HI, Young RA, Sharp PA#.
    Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis.
    Cell. 2017 Mar 9;168(6):1000-1014.e15. doi: 10.1016/j.cell.2017.02.015.

2016

  1. Horie M, Saito A#, Ohshima M, Suzuki HI, Nagase T.
    YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.
    Cancer Sci. 2016 Dec;107(12):1755-1766. doi: 10.1111/cas.13078. Epub 2016 Nov 25.
  2. Katsura A, Suzuki HI#, Ueno T, Mihira H, Yamazaki T, Yasuda T, Watabe T, Mano H, Yamada Y, Miyazono K#.
    MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced
    by TGF-β.
    Genes Cells. 2016 Jan;21(1):99-116. doi: 10.1111/gtc.12323. Epub 2015 Dec 10.

2015

  1. Shichino S, Abe J, Ueha S, Otsuji M, Tsukui T, Kosugi-Kanaya M, Shand FH, Hashimoto S, Suzuki HI, Morikawa T, Inagaki Y, Matsushima K#.
    Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.
    Am J Pathol. 2015 Nov;185(11):2923-38. doi: 10.1016/j.ajpath.2015.07.013. Epub 2015 Oct 9.
  2. Sugimoto K*, Suzuki HI*#, Fujimura T, Ono A, Kaga N, Isobe Y, Sasaki M, Taka H, Miyazono K, Komatsu N.
    A clinically attainable dose of L-asparaginase targets glutamine addiction in lymphoid cell lines.
    Cancer Sci. 2015 Nov;106(11):1534-43. doi: 10.1111/cas.12807. Epub 2015 Oct 16. (* equal contribution)
  3. Suzuki HI#, Katsura A, Yasuda T, Ueno T, Mano H, Sugimoto K, Miyazono K#.
    Small-RNA asymmetry is directly driven by mammalian Argonautes.
    Nat Struct Mol Biol. 2015 Jul;22(7):512-21. doi: 10.1038/nsmb.3050. Epub 2015 Jun 22.
  4. Suzuki HI#, Katsura A, Miyazono K.
    A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B.
    Cancer Sci. 2015 Sep;106(9):1174-81. doi: 10.1111/cas.12721. Epub 2015 Jul 14.
  5. Itami S, Eguchi Y, Mizutani T, Aoki E, Ohgi T, Kuroda M, Ochiya T, Kato N, Suzuki HI, Kawada N, Murakami Y#.
    Control of HCV Replication With iMIRs, a Novel Anti-RNAi Agent.
    Mol Ther Nucleic Acids. 2015;4:e219. doi: 10.1038/mtna.2014.71. Epub 2016 Dec 6.
  6. Suzuki HI, Katsura A, Matsuyama H, Miyazono K#.
    MicroRNA regulons in tumor microenvironment.
    Oncogene. 2015 Jun 11;34(24):3085-94. doi: 10.1038/onc.2014.254. Epub 2014 Aug 18.

2014

  1. Horie M, Saito A#, Noguchi S, Yamaguchi Y, Ohshima M, Morishita Y, Suzuki HI, Kohyama T, Nagase T.
    Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer.
    BMC Cancer. 2014 Aug 9;14:580. doi: 10.1186/1471-2407-14-580.
  2. Noguchi S, Saito A#, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M, Edlund K, Botling J, Micke P, Nagase T.
    An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.
    Clin Cancer Res. 2014 Sep 1;20(17):4660-72. doi: 10.1158/1078-0432.CCR-13-3328. Epub 2014 Jun 20.
  3. Tanaka M, Suzuki HI, Shibahara J, Kunita A, Isagawa T, Yoshimi A, Kurokawa M, Miyazono K, Aburatani H, Ishikawa S, Fukayama M#.
    EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis.
    Oncogene. 2014 May 8;33(19):2454-63. doi: 10.1038/onc.2013.204. Epub 2013 Jun 10.

2013

  1. Yoshimatsu Y, Lee YG, Akatsu Y, Taguchi L, Suzuki HI, Cunha SI, Maruyama K, Suzuki Y, Yamazaki T, Katsura A, Oh SP, Zimmers TA, Lee SJ, Pietras K, Koh GY, Miyazono K#, Watabe T.
    Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.
    Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18940-5. doi: 10.1073/pnas.1310479110. Epub 2013 Oct 16.
  2. Suzuki HI#, Matsuyama H, Noguchi M, Yao T, Komatsu N, Mano H, Sugimoto K, Miyazono K#.
    Computational dissection of distinct microRNA activity signatures associated with peripheral T cell lymphoma subtypes.
    Leukemia. 2013 Oct;27(10):2107-11. doi: 10.1038/leu.2013.121. Epub 2013 Apr 18.
  3. Saito A#, Suzuki HI, Horie M, Ohshima M, Morishita Y, Abiko Y, Nagase T.
    An integrated expression profiling reveals target genes of TGF-β and TNF-α possibly mediated by microRNAs in lung cancer cells.
    PLoS One. 2013;8(2):e56587. doi: 10.1371/journal.pone.0056587. Epub 2013 Feb 20.
  4. Suzuki HI#, Mihira H, Watabe T, Sugimoto K, Miyazono K#.
    Widespread inference of weighted microRNA-mediated gene regulation in cancer transcriptome analysis.
    Nucleic Acids Res. 2013 Mar 1;41(5):e62. doi: 10.1093/nar/gks1439. Epub 2012 Dec 28.
  5. Suzuki HI, Miyazono K#.
    p53 actions on microRNA expression and maturation pathway.
    Methods Mol Biol. 2013;962:165-81. doi: 10.1007/978-1-62703-236-0_14.
  6. Liang C, Xiong K, Szulwuch KE, Zhang Y, Wang Z, Peng J, Fu M, Jin P, Suzuki HI, Liu Q#.
    Sjogren syndrome antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition.
    J Biol Chem. 2013 Jan 4;288(1):723-36. doi: 10.1074/jbc.M112.401323. Epub 2012 Nov 5.

2012

  1. Suzuki HI, Miyazono K#.
    Control of MicroRNA Maturation by p53 Tumor Suppressor and MCPIP1 Ribonuclease.
    The Enzymes. 2012;32:163-183. doi: 10.1016/B978-0-12-404741-9.00008-8
  2. Nishimori H, Ehata S#, Suzuki HI, Katsuno Y, Miyazono K#.
    Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals.
    J Biol Chem. 2012 Jun 8;287(24):20037-46. doi: 10.1074/jbc.M112.353094. Epub 2012 Apr 24.
  3. Mihira H, Suzuki HI, Akatsu Y, Yoshimatsu Y, Igarashi T, Miyazono K, Watabe T#.
    TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A.
    J Biochem. 2012 Feb;151(2):145-56. doi: 10.1093/jb/mvr121. Epub 2011 Oct 8.

2011

  1. Suzuki HI, Arase M, Matsuyama H, Choi YL, Ueno T, Mano H, Sugimoto K, Miyazono K#.
    MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation.
    Mol Cell. 2011 Nov 4;44(3):424-36. doi: 10.1016/j.molcel.2011.09.012.
  2. Matsuyama H*, Suzuki HI*, Nishimori H, Noguchi M, Yao T, Komatsu N, Mano H, Sugimoto K, Miyazono K#.
    miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma.
    Blood. 2011 Dec 22;118(26):6881-92. doi: 10.1182/blood-2011-05-354654. Epub 2011 Oct 31.
  3. Mizutani A, Koinuma D, Tsutsumi S, Kamimura N, Morikawa M, Suzuki HI, Imamura T, Miyazono K#, Aburatani H.
    Cell type-specific target selection by combinatorial binding of Smad2/3 proteins and hepatocyte nuclear factor 4alpha in HepG2 cells.
    J Biol Chem. 2011 Aug 26;286(34):29848-60. doi: 10.1074/jbc.M110.217745. Epub 2011 Jun 6.
  4. Suzuki HI, Miyazono K#.
    Emerging complexity of microRNA generation cascades.
    J Biochem. 2011 Jan;149(1):15-25. doi: 10.1093/jb/mvq113. Epub 2010 Sep 27.

2010

  1. Suzuki HI, Miyazono K#.
    Dynamics of microRNA biogenesis: crosstalk between p53 network and microRNA processing pathway.
    J Mol Med (Berl). 2010 Nov;88(11):1085-94. doi: 10.1007/s00109-010-0650-1. Epub 2010 Jul 8.
  2. Suzuki HI, Kiyono K, Miyazono K#.
    Regulation of autophagy by transforming growth factor-β (TGF-β) signaling.
    Autophagy. 2010 Jul;6(5):645-7. doi: 10.4161/auto.6.5.12046. Epub 2010 Jul 1.
  3. Hosoi M, Nannya Y, Sasaki T, Suzuki HI, Ueda K, Tsujino T, Isayama H, Takahashi T, Koike K, and Kurokawa M#.
    Biliary cast syndrome and benign biliary stricture as complications of allogeneic hematopoietic stem cell transplantation.
    Ann Hematol. 2010 Dec;89(12):1287-9. doi: 10.1007/s00277-010-0942-0. Epub 2010 Mar 30.
  4. Suzuki HI, Hosoya N, Miyagawa K, Ota S, Nakashima H, Makita N, Kurokawa M#.
    Erdheim-Chester disease: multisystem involvement and management with interferon-alpha.
    Leuk Res. 2010 Jan;34(1):e21-4. doi: 10.1016/j.leukres.2009.07.026. Epub 2009 Aug 12.

2009

  1. Kiyono K*, Suzuki HI*, Matsuyama H, Morishita Y, Komuro A, Kano M, Sugimoto K, Miyazono K#.
    Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells.
    Cancer Res. 2009 Dec 1;69(23):8844-52. doi: 10.1158/0008-5472.CAN-08-4401. Epub 2009 Nov 10.
  2. Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, Miyazono K#.
    Modulation of microRNA processing by p53.
    Nature. 2009 Jul 23;460(7254):529-33. doi: 10.1038/nature08199.
  3. Kiyono K, Suzuki HI, Morishita Y, Komuro A, Iwata C, Yashiro M, Hirakawa K, Kano MR, Miyazono K#.
    c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-beta signaling in diffuse-type gastric carcinoma.
    Cancer Sci. 2009 Oct;100(10):1809-16. doi: 10.1111/j.1349-7006.2009.01248.x. Epub 2009 Jun 17.
  4. Komuro A, Yashiro M, Iwata C, Morishita Y, Johansson E, Matsumoto Y, Watanabe A, Aburatani H, Miyoshi H, Kiyono K, Shirai YT, Suzuki HI, Hirakawa K, Kano MR, Miyazono K#.
    Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling.
    J Natl Cancer Inst. 2009 Apr 15;101(8):592-604. doi: 10.1093/jnci/djp058. Epub 2009 Apr 7.

2008

  1. Suzuki H, Tsurita G#, Ishihara S, Akahane M, Kitayama J, Nagawa H.
    Resovist-enhanced MRI for preoperative assessment of colorectal hepatic metastases: a case of multiple bile duct hamartomas associated with colon cancer.
    Case Rep Gastroenterol. 2008 Sep;2(3):509-16. doi: 10.1159/000183536. Epub 2008 Dec 10.
  2. Suzuki HI, Izutsu K, Watanabe T, Oshima K, Kanda Y, Motokura T, Chiba S, Kurokawa M#.
    Late-onset pneumatosis cystoides intestinalis associated with non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation.
    Int J Hematol. 2008 Jul;88(1):116-118. doi: 10.1007/s12185-008-0110-7. Epub 2008 Jun 17.
  3. Suzuki HI, Suzuki T, Kamijo A, Oota S, Sato H, Hangaishi A, Takahashi T, Kanda Y, Motokura T, Chiba S, Kurokawa M#.
    Antileukemic immunity associated with antineutrophil antibody production after allogeneic hematopoietic SCT for myeloid/NK-cell precursor acute leukemia.
    Bone Marrow Transplant. 2008 Aug;42(4):285-7. doi: 10.1038/bmt.2008.158. Epub 2008 May 26.
  4. Suzuki HI, Hangaishi A, Hosoya N, Watanabe T, Kanda Y, Motokura T, Chiba S, Kurokawa M#.
    Herpes simplex encephalitis and subsequent cytomegalovirus encephalitis after chemoradiotherapy for central nervous system lymphoma: a case report and literature review.
    Int J Hematol. 2008 Jun;87(5):538-541. doi: 10.1007/s12185-008-0083-6. Epub 2008 Apr 17.
  5. Suzuki HI, Asai T, Tamaki Z, Hangaishi A, Chiba S, Kurokawa M#.
    Drug-induced hypersensitivity syndrome with rapid hematopoietic reconstitution during treatment for acute myeloid leukemia.
    Haematologica. 2008 Mar;93(3):469-70. doi: 10.3324/haematol.12029.
  6. Oka M, Iwata C, Suzuki HI, Kiyono K, Morishita Y, Watabe T, Komuro A, Kano MR, Miyazono K#.
    Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis.
    Blood. 2008 May 1;111(9):4571-9. doi: 10.1182/blood-2007-10-120337. Epub 2008 Feb 29.
  7. Suzuki HI, Asai T, Okada K, Kazuyama Y, Takahashi T, Kanda Y, Chiba S, Kurokawa M#.
    Disseminated adenovirus disease by multiple adenovirus serotypes following allogeneic hematopoietic stem cell transplantation.
    Biol Blood Marrow Transplant. 2008 Mar;14(3):353-5. doi: 10.1016/j.bbmt.2007.12.001.

2007

  1. Ogawa K, Saito A, Matsui H, Suzuki H, Ohtsuka S, Shimosato D, Morishita Y, Watabe T, Niwa H#, Miyazono K#.
    Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells.
    J Cell Sci. 2007 Jan 1;120(Pt 1):55-65. doi: 10.1242/jcs.03296.

2002

  1. Takayanagi H, Kim S, Matsuo K, Suzuki H, Suzuki T, Sato K, Yokochi T, Oda H, Nakamura K, Ida N, Wagner EF, Taniguchi T#.
    RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta.
    Nature. 2002 Apr 18;416(6882):744-9. doi: 10.1038/416744a.